| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50312953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_616078 (CHEMBL1102041) |
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| Ki | 78±n/a nM |
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| Citation |  Eastwood, P; Gonzalez, J; Paredes, S; Nueda, A; Domenech, T; Alberti, J; Vidal, B Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists. Bioorg Med Chem Lett20:1697-700 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50312953 |
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| n/a |
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| Name | BDBM50312953 |
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| Synonyms: | CHEMBL1082171 | N-(2-(thiazol-5-yl)-3,4'-bipyridin-6-yl)cyclopropanecarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N4OS |
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| Mol. Mass. | 322.384 |
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| SMILES | O=C(Nc1ccc(-c2ccncc2)c(n1)-c1cncs1)C1CC1 |
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| Structure | 
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