| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50321767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_641177 (CHEMBL1174684) |
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| Ki | 9±n/a nM |
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| Citation |  Oberdorf, C; Schmidt, TJ; Wünsch, B 5D-QSAR for spirocyclic sigma1 receptor ligands by Quasar receptor surface modeling. Eur J Med Chem45:3116-24 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50321767 |
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| n/a |
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| Name | BDBM50321767 |
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| Synonyms: | (R)-2-(1'-(cyclohexylmethyl)spiro[isochroman-1,4'-piperidine]-3-yl)ethanol | CHEMBL1171865 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H33NO2 |
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| Mol. Mass. | 343.5029 |
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| SMILES | OCC[C@H]1Cc2ccccc2C2(CCN(CC3CCCCC3)CC2)O1 |r| |
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| Structure | 
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