| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50349862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_760691 (CHEMBL1815676) |
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| Ki | 1311±n/a nM |
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| Citation |  Vangveravong, S; Zhang, Z; Taylor, M; Bearden, M; Xu, J; Cui, J; Wang, W; Luedtke, RR; Mach, RH Synthesis and characterization of selective dopamine D2 receptor ligands using aripiprazole as the lead compound. Bioorg Med Chem19:3502-11 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50349862 |
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| n/a |
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| Name | BDBM50349862 |
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| Synonyms: | CHEMBL1813586 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29ClN2O3 |
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| Mol. Mass. | 428.952 |
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| SMILES | OC1(CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1)c1ccc(Cl)cc1 |
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| Structure | 
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