| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50355325 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_772926 (CHEMBL1838814) |
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| IC50 | 0.74±n/a nM |
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| Citation |  Matos, MJ; Terán, C; Pérez-Castillo, Y; Uriarte, E; Santana, L; Viña, D Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors. J Med Chem54:7127-37 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM50355325 |
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| n/a |
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| Name | BDBM50355325 |
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| Synonyms: | CHEMBL1835231 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13BrO3 |
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| Mol. Mass. | 345.187 |
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| SMILES | COc1ccc(cc1Br)-c1cc2cc(C)ccc2oc1=O |
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| Structure | 
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