| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 1 |
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| Ligand | BDBM50358671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_789438 (CHEMBL1924414) |
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| IC50 | 6820±n/a nM |
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| Citation |  Sagi, VN; Liu, T; Lu, X; Bartfai, T; Roberts, E Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2. Bioorg Med Chem Lett21:7210-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 1 |
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| Name: | Galanin receptor type 1 |
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| Synonyms: | GAL1-R | GALNR | GALNR1 | GALR1 | GALR1_HUMAN | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38976.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Galanin R1 GALR1 HUMAN::P47211 |
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| Residue: | 349 |
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| Sequence: | MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLAR
SKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSML
VSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR
ASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEA
SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNP
IIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
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| BDBM50358671 |
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| n/a |
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| Name | BDBM50358671 |
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| Synonyms: | CHEMBL1922023 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29FN6O2 |
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| Mol. Mass. | 500.5673 |
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| SMILES | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(n2)N2CCN(CC2)c2ccccc2)cc1 |
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| Structure | 
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