Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50360143 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_793539 (CHEMBL1932290) |
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Ki | 13±n/a nM |
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Citation | Ida, Y; Nemoto, T; Hirayama, S; Fujii, H; Osa, Y; Imai, M; Nakamura, T; Kanemasa, T; Kato, A; Nagase, H Synthesis of quinolinomorphinan-4-ol derivatives asd opioid receptor agonists. Bioorg Med Chem20:949-61 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50360143 |
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n/a |
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Name | BDBM50360143 |
Synonyms: | CHEMBL1929363 |
Type | Small organic molecule |
Emp. Form. | C27H26N2O2 |
Mol. Mass. | 410.5075 |
SMILES | Oc1ccc2C[C@@H]3[C@@H]4Cc5cc6ccccc6nc5[C@@H]5Oc1c2[C@]45CCN3CC1CC1 |r| |
Structure |
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