| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT8 |
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| Ligand | BDBM50360449 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_796800 (CHEMBL1938115) |
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| IC50 | 47000±n/a nM |
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| Citation |  Ghizzoni, M; Wu, J; Gao, T; Haisma, HJ; Dekker, FJ; George Zheng, Y 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur J Med Chem47:337-44 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT8 |
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| Name: | Histone acetyltransferase KAT8 |
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| Synonyms: | KAT8 | KAT8_HUMAN | Lysine acetyltransferase 8 | MOF | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 | MYST-1 | MYST1 | hMOF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52413.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_796800 |
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| Residue: | 458 |
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| Sequence: | MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
LVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
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| BDBM50360449 |
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| n/a |
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| Name | BDBM50360449 |
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| Synonyms: | CHEMBL1215739 | MG-149 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28O3 |
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| Mol. Mass. | 340.4559 |
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| SMILES | CCCCCCCc1ccc(CCc2cccc(O)c2C(O)=O)cc1 |
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| Structure | 
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