| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50282623 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36775 (CHEMBL650297) |
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| IC50 | 5500±n/a nM |
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| Citation |  Dorsch, D; Mederski, WW; Beier, N; Lues, I; Minck, K; Schelling, P (6-oxo-3-pyridazinyl)-benzimidazoles as potent angiotensin II receptor antagonists Bioorg Med Chem Lett4:1297-1302 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41107.81 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_36779 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
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| BDBM50282623 |
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| n/a |
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| Name | BDBM50282623 |
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| Synonyms: | 6-{2-(4-Methoxy-phenyl)-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-benzoimidazol-5-yl}-5-methyl-4,5-dihydro-2H-pyridazin-3-one | CHEMBL284546 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H28N8O2 |
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| Mol. Mass. | 568.6278 |
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| SMILES | COc1ccc(cc1)-c1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C1=NNC(=O)CC1C |t:41| |
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| Structure | 
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