| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50088424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_31699 |
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| Ki | 170±n/a nM |
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| Citation |  Lee, K; Ravi, G; Ji, XD; Marquez, VE; Jacobson, KA Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications. Bioorg Med Chem Lett11:1333-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50088424 |
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| n/a |
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| Name | BDBM50088424 |
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| Synonyms: | (1R,2R,3S,4R,5S)-4-(6-Cyclopentylamino-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol | 4-(6-Cyclopentylamino-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol | CHEMBL27952 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23N5O3 |
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| Mol. Mass. | 345.3962 |
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| SMILES | OC[C@@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NC3CCCC3)ncnc12 |
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| Structure | 
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