| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50034908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_30789 |
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| Ki | 10±n/a nM |
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| Citation |  Wang, L; Hosmane, RS A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine. Bioorg Med Chem Lett11:2893-6 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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| BDBM50034908 |
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| n/a |
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| Name | BDBM50034908 |
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| Synonyms: | (2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2R,3S)-3-(6-Amino-purin-9-yl)-nonan-2-ol | (2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | (EHNA)3-(6-Amino-purin-9-yl)-nonan-2-ol | 3-(6-Amino-purin-9-yl)-nonan-2-ol | 3-(6-Amino-purin-9-yl)-nonan-2-ol(EHNA) | CHEMBL50378 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H23N5O |
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| Mol. Mass. | 277.3653 |
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| SMILES | CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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