Reaction Details | |||
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Target | D(2) dopamine receptor | ||
Ligand | BDBM50007422 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_59782 (CHEMBL671063) | ||
IC50 | 0.000±n/a nM | ||
Citation | Neumeyer, JL; Guan, JH; Niznik, HB; Dumbrille-Ross, A; Seeman, P; Padmanabhan, S; Elmaleh, DR Novel photoaffinity label for the dopamine D2 receptor: synthesis of 4-azido-5-iodo-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl] benzamide (iodoazidoclebopride, IAC) and the corresponding 125I-labeled analogue (125IAC). J Med Chem28:405-7 (1985) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
D(2) dopamine receptor | |||
Name: | D(2) dopamine receptor | ||
Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
Type: | Cell-surface receptors | ||
Mol. Mass.: | 50647.10 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P14416 | ||
Residue: | 443 | ||
Sequence: |
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BDBM50007422 | |||
n/a | |||
Name | BDBM50007422 | ||
Synonyms: | (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | (-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | (R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | (R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium | (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA) | 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | CHEMBL225230 | CHEMBL538542 | N-propylapomorphine | N-propylnorapomorphine-(+) | N-propylnorapomorphine-(-) | ||
Type | Small organic molecule | ||
Emp. Form. | C19H21NO2 | ||
Mol. Mass. | 295.3755 | ||
SMILES | CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| | ||
Structure |