| Reaction Details |
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 | Report a problem with these data |
| Target | Chitin synthase 1 |
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| Ligand | BDBM50367321 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_49250 (CHEMBL660670) |
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| Ki | 1060000±n/a nM |
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| Citation |  Shenbagamurthi, P; Smith, HA; Becker, JM; Naider, F Synthesis and biological properties of chitin synthetase inhibitors resistant to cellular peptidases. J Med Chem29:802-9 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitin synthase 1 |
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| Name: | Chitin synthase 1 |
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| Synonyms: | CHS1 | CHS1_CANAX | Chitin synthase | Chitin synthase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88249.31 |
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| Organism: | Candida albicans |
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| Description: | ChEMBL_49240 |
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| Residue: | 776 |
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| Sequence: | MHNINNGYVPNREKTITKRKVRLVGGKAGNLVLENPVPTELRKVLTRTESPFGEFTNMTY
TACTSQPDTFSAEGFTLRAAKYGRETEIVICITMYNEDEVAFARTMHGVMKNIAHLCSRH
KSKIWGKDSWKKVQVIIVADGRNKVQQSVLELLTATGCYQENLARPYVNNSKVNAHLFEY
TTQISIDENLKFKGDEKNLAPVQVLFCLKESNQKKINSHRWLFNAFCPVLDPNVIVLLDV
GTKPDNHAIYNLWKAFDRDSNVAGAAGEIKAMKGKGWINLTNPLVASQNFEYKLSNILDK
PLESLFGYISVLPGALSAYRYIALKNHDDGTGPLASYFKGEDLLCSHDKDKENTKANFFE
ANMYLAEDRILCWELVSKRNDNWVLKFVKSATGETDVPETIAEFLSQRRRWINGAFFAAL
YSLYHFRKIWTTDHSYARKFWLHVEEFIYQLVSLLFSFFSLSNFYLTFYFLTGSLVSYKS
LGKKGGFWIFTLFNYLCIGVLTSLFIVSIGNRPHASKNIFKTLIILLTICALYALVVGFV
FVINTIATFGTGGTSTYVLVSIVVSLLSTYGLYTLMSILYLDPWHMLTCSVQYFLMIPSY
TCTLQIFAFCNTHDVSWGTKGDNNPKEDLSNQYIIEKNASGEFEAVIVDTNIDEDYLETL
YNIRSKRSNKKVALGHSEKTPLDGDDYAKDVRTRVVLFWMIANLVFIMTMVQVYEPGDTG
RNIYLAFILWAVAVLALVRAIGSLGYLIQTYARFFVESKSKWMKRGYTAPSHNPLN
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| BDBM50367321 |
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| n/a |
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| Name | BDBM50367321 |
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| Synonyms: | CHEMBL1791439 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23N5O8 |
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| Mol. Mass. | 473.436 |
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| SMILES | N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)C(O)=O |r| |
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| Structure | 
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