| Reaction Details |
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 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
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| Ligand | BDBM50024843 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153309 |
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| Ki | 487000±n/a nM |
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| Citation |  Sall, DJ; Grunewald, GL Inhibition of phenylethanolamine N-methyltransferase (PNMT) by aromatic hydroxy-substituted 1,2,3,4,-tetrahydroisoquinolines: further studies on the hydrophilic pocket of the aromatic ring binding region of the active site. J Med Chem30:2208-16 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phenylethanolamine N-methyltransferase |
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| Name: | Phenylethanolamine N-methyltransferase |
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| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
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| Type: | Enzyme |
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| Mol. Mass.: | 30916.97 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 283 |
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| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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| BDBM50024843 |
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| n/a |
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| Name | BDBM50024843 |
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| Synonyms: | 2-Amino-1,2,3,4-tetrahydro-1,4-methano-naphthalene-6,7-diol | CHEMBL61595 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13NO2 |
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| Mol. Mass. | 191.2264 |
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| SMILES | N[C@@H]1CC2CC1c1cc(O)c(O)cc21 |TLB:0:1:6.13:4,THB:7:6:4:1.2,12:13:4:1.2| |
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| Structure | 
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