| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 [K65Q] |
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| Ligand | BDBM50022498 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_31633 |
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| IC50 | 1000±n/a nM |
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| Citation |  Sarges, R; Schnur, RC; Belletire, JL; Peterson, MJ Spiro hydantoin aldose reductase inhibitors. J Med Chem31:230-43 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldo-keto reductase family 1 member B1 [K65Q] |
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| Name: | Aldo-keto reductase family 1 member B1 [K65Q] |
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| Synonyms: | AKR1B1 | ALDR_BOVIN | Aldose reductase |
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| Type: | Protein |
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| Mol. Mass.: | 35916.27 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | P16116[K65Q] |
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| Residue: | 315 |
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| Sequence: | AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQA
KLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKD
FFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPA
VNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKY
NKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACAL
VSCASHRDYPFHEEF
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| BDBM50022498 |
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| n/a |
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| Name | BDBM50022498 |
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| Synonyms: | 6-Chloro-3,4-dihydro-2H-benzo[h]chromene-4-carboxylic acid | CHEMBL82424 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11ClO3 |
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| Mol. Mass. | 262.688 |
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| SMILES | OC(=O)C1CCOc2c1cc(Cl)c1ccccc21 |
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| Structure | 
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