| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50004594 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29421 |
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| Ki | 81±n/a nM |
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| Citation |  Suzuki, F; Shimada, J; Mizumoto, H; Karasawa, A; Kubo, K; Nonaka, H; Ishii, A; Kawakita, T Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure. J Med Chem35:3066-75 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36501.39 |
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| Organism: | GUINEA PIG |
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| Description: | ADENOSINE A1 ADORA1 GUINEA PIG::P47745 |
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| Residue: | 326 |
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| Sequence: | MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPEPPIDEDLPEEKVDD
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| BDBM50004594 |
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| n/a |
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| Name | BDBM50004594 |
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| Synonyms: | 8-Dicyclopropylmethyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione | CHEMBL106937 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N4O2 |
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| Mol. Mass. | 274.3183 |
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| SMILES | Cn1c2nc([nH]c2c(=O)n(C)c1=O)C(C1CC1)C1CC1 |
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| Structure | 
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