| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin D |
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| Ligand | BDBM50368801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_44982 (CHEMBL660143) |
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| IC50 | >10000±n/a nM |
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| Citation |  Shiosaki, K; Tasker, AS; Sullivan, GM; Sorensen, BK; von Geldern, TW; Wu-Wong, JR; Marselle, CA; Opgenorth, TJ Potent and selective inhibitors of an aspartyl protease-like endothelin converting enzyme identified in rat lung. J Med Chem36:468-78 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin D |
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| Name: | Cathepsin D |
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| Synonyms: | CATD_BOVIN | CTSD |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42158.92 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1458606 |
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| Residue: | 387 |
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| Sequence: | VIRIPLHKFTSIRRTMSEAAGVLIAKGPISKYATGEPAVRQGPIPELLKNYMDAQYYGEI
GIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSSTYVKNGTTFDIHYG
SGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVFIAAKFDGILGMAYPR
ISVNNVLPVFDNLMQQKLVDKNVFSFFLNRDPKAQPGGELMLGGTDSKYYRGSLMFHNVT
RQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLIVGPVEEVRELQKAIGAVPLIQGEY
MIPCEKVSSLPEVTVKLGGKDYALSPEDYALKVSQAETTVCLSGFMGMDIPPPGGPLWIL
GDVFIGRYYTVFDRDQNRVGLAEAARL
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| BDBM50368801 |
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| n/a |
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| Name | BDBM50368801 |
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| Synonyms: | CHEMBL1791114 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H58N6O11 |
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| Mol. Mass. | 774.9007 |
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| SMILES | CC[C@@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(O)=O)[C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)CC(=O)N[C@@H](C(C)C)C(O)=O |
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| Structure | 
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