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TargetPlatelet-activating factor receptor
LigandBDBM50034220
Substrate/Competitorn/a
Meas. Tech.ChEMBL_162891 (CHEMBL768221)
Temperature310.15±n/a K
IC50>200000±n/a nM
Commentsextracted
Citation Fos, E; Suesa, N; Borras, L; Lobato, C; Banfi, P; Gambetta, RA; Zunino, F; Mauleón, D; Carganico, G Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity. J Med Chem38:1216-28 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet-activating factor receptor
Name:Platelet-activating factor receptor
Synonyms:PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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  Blast E-value cutoff:
BDBM50034220
n/a
NameBDBM50034220
Synonyms:2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide | CHEMBL125 | MILTEFOSINE | [2-(Hexadecyloxy-hydroxy-phosphoryloxy)-ethyl]-trimethyl-ammonium | hexadecyl 2-(trimethyl-lambda~5~-azanyl)ethyl hydrogen phosphate | hexadecyl 2-(trimethylammonio)ethyl phosphate | hexadecyloxy-2-trimethylammonioethylphosphorate | hexadecylphosphocholine | hexadecylphosphocholine, miltefosine | n-hexadecylphosphocholine
TypeSmall organic molecule
Emp. Form.C21H46NO4P
Mol. Mass.407.568
SMILESCCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C
Structure
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