| Reaction Details |
|---|
 | Report a problem with these data |
| Target | L-selectin |
|---|
| Ligand | BDBM50060515 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200000 (CHEMBL810689) |
|---|
| IC50 | 1800±n/a nM |
|---|
| Citation |  Tsukida, T; Moriyama, H; Kurokawa, K; Achiha, T; Inoue, Y; Kondo, H Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides. J Med Chem41:4279-87 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| L-selectin |
|---|
| Name: | L-selectin |
|---|
| Synonyms: | LNHR | LYAM1 | LYAM1_HUMAN | Leukocyte adhesion molecule-1 | SELL | Selectin |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 42187.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_200000 |
|---|
| Residue: | 372 |
|---|
| Sequence: | MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN
YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN
NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC
NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT
CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK
TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK
GKKSKRSMNDPY
|
|
|
|---|
| BDBM50060515 |
|---|
| n/a |
|---|
| Name | BDBM50060515 |
|---|
| Synonyms: | (S)-4-Methylcarbamoyl-4-[(S)-2-(2-tetradecyl-hexadecanoylamino)-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-propionylamino]-butyric acid | (S)-4-Methylcarbamoyl-4-[2-((S)-2-tetradecyl-hexadecanoylamino)-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-propionylamino]-butyric acid | CHEMBL76801 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C45H85N3O10 |
|---|
| Mol. Mass. | 828.1705 |
|---|
| SMILES | CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)C(=O)N[C@@H](COC1OC(C)C(O)C(O)C1O)C(=O)N[C@@H](CCC(O)=O)C(=O)NC |
|---|
| Structure | 
|
|---|
Search and Browse
