| Reaction Details |
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 | Report a problem with these data |
| Target | MO15-related protein kinase Pfmrk |
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| Ligand | BDBM50132005 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_52684 (CHEMBL666139) |
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| IC50 | 17100±n/a nM |
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| Citation |  Woodard, CL; Li, Z; Kathcart, AK; Terrell, J; Gerena, L; Lopez-Sanchez, M; Kyle, DE; Bhattacharjee, AK; Nichols, DA; Ellis, W; Prigge, ST; Geyer, JA; Waters, NC Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases. J Med Chem46:3877-82 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| MO15-related protein kinase Pfmrk |
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| Name: | MO15-related protein kinase Pfmrk |
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| Synonyms: | Protein kinase Pfmrk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37992.30 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_640752 |
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| Residue: | 324 |
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| Sequence: | MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLL
REIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQI
LNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLN
LTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFL
LGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAED
AMKHRYFFNDPLPCDISQLPFNDL
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| BDBM50132005 |
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| n/a |
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| Name | BDBM50132005 |
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| Synonyms: | 5-Methoxy-3-(4-oxo-2-thioxo-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one | 5-methoxy-3-(4-oxo-2-thioxothiazolidin-5-ylidene)indolin-2-one | CHEMBL130414 | CHEMBL362785 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8N2O3S2 |
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| Mol. Mass. | 292.334 |
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| SMILES | COc1ccc2NC(=O)C(=C3SC(S)=NC3=O)c2c1 |w:10.15,c:13| |
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| Structure | 
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