| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50155523 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_302618 |
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| Ki | 345±n/a nM |
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| Citation |  Sikazwe, DM; Li, S; Mardenborough, L; Cody, V; Roth, BL; Ablordeppey, SY Haloperidol: towards further understanding of the structural contributions of its pharmacophoric elements at D2-like receptors. Bioorg Med Chem Lett14:5739-42 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50155523 |
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| n/a |
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| Name | BDBM50155523 |
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| Synonyms: | 4-[3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride | CHEMBL537182 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClFNO |
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| Mol. Mass. | 385.902 |
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| SMILES | Fc1ccc(cc1)C(=O)CCCN1C2CCC1CC(C2)c1ccc(Cl)cc1 |TLB:11:12:18.19.17:14.15| |
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| Structure | 
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