| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50182579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_334933 (CHEMBL859253) |
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| IC50 | >10000±n/a nM |
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| Citation |  Meltzer, PC; Butler, D; Deschamps, JR; Madras, BK 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors. J Med Chem49:1420-32 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50182579 |
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| n/a |
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| Name | BDBM50182579 |
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| Synonyms: | CHEMBL379679 | N-[4-(2-pyrrolidin-1-yl-pentanoyl)phenyl]acetamide | N-[4-(2-pyrrolidin-1-yl-pentanoyl)phenylacetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H24N2O2 |
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| Mol. Mass. | 288.3847 |
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| SMILES | CCCC(N1CCCC1)C(=O)c1ccc(NC(C)=O)cc1 |
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| Structure | 
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