| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50182579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_334935 (CHEMBL859255) |
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| IC50 | >10000±n/a nM |
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| Citation |  Meltzer, PC; Butler, D; Deschamps, JR; Madras, BK 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors. J Med Chem49:1420-32 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50182579 |
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| n/a |
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| Name | BDBM50182579 |
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| Synonyms: | CHEMBL379679 | N-[4-(2-pyrrolidin-1-yl-pentanoyl)phenyl]acetamide | N-[4-(2-pyrrolidin-1-yl-pentanoyl)phenylacetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H24N2O2 |
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| Mol. Mass. | 288.3847 |
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| SMILES | CCCC(N1CCCC1)C(=O)c1ccc(NC(C)=O)cc1 |
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| Structure | 
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