| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucose 4-epimerase |
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| Ligand | BDBM20625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_424499 (CHEMBL911909) |
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| IC50 | 75000±n/a nM |
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| Citation |  Urbaniak, MD; Tabudravu, JN; Msaki, A; Matera, KM; Brenk, R; Jaspars, M; Ferguson, MA Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness. Bioorg Med Chem Lett16:5744-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucose 4-epimerase |
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| Name: | UDP-glucose 4-epimerase |
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| Synonyms: | GALE | GALE_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38282.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_424499 |
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| Residue: | 348 |
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| Sequence: | MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
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| BDBM20625 |
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| n/a |
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| Name | BDBM20625 |
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| Synonyms: | 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | 4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | CHEMBL411 | Diethylstilbestrol | Diethylstilbestrol (1) | Stilbestrol | Stilboestroform |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20O2 |
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| Mol. Mass. | 268.3502 |
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| SMILES | CC\C(=C(\CC)c1ccc(O)cc1)c1ccc(O)cc1 |
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| Structure | 
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