| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucose 4-epimerase |
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| Ligand | BDBM50194601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_424499 (CHEMBL911909) |
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| IC50 | 500±n/a nM |
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| Citation |  Urbaniak, MD; Tabudravu, JN; Msaki, A; Matera, KM; Brenk, R; Jaspars, M; Ferguson, MA Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness. Bioorg Med Chem Lett16:5744-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucose 4-epimerase |
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| Name: | UDP-glucose 4-epimerase |
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| Synonyms: | GALE | GALE_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38282.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_424499 |
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| Residue: | 348 |
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| Sequence: | MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
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| BDBM50194601 |
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| n/a |
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| Name | BDBM50194601 |
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| Synonyms: | 1,2,4-Trichloro-5-(3-iodo-prop-2-ynyloxy)-benzene | 1,2,4-trichloro-5-(3-iodoprop-2-ynyloxy)benzene | CHEMBL1289 | HALOPROGIN | Halotex | M-1028 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H4Cl3IO |
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| Mol. Mass. | 361.391 |
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| SMILES | Clc1cc(Cl)c(OCC#CI)cc1Cl |
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| Structure | 
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