| Reaction Details |
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 | Report a problem with these data |
| Target | Acyl-CoA desaturase 1 |
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| Ligand | BDBM50371076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_438936 (CHEMBL889279) |
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| IC50 | 950±n/a nM |
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| Citation |  Liu, G; Lynch, JK; Freeman, J; Liu, B; Xin, Z; Zhao, H; Serby, MD; Kym, PR; Suhar, TS; Smith, HT; Cao, N; Yang, R; Janis, RS; Krauser, JA; Cepa, SP; Beno, DW; Sham, HL; Collins, CA; Surowy, TK; Camp, HS Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors. J Med Chem50:3086-100 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acyl-CoA desaturase 1 |
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| Name: | Acyl-CoA desaturase 1 |
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| Synonyms: | ACOD1_MOUSE | Scd1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41064.54 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1462109 |
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| Residue: | 355 |
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| Sequence: | MPAHMLQEISSSYTTTTTITAPPSGNEREKVKTVPLHLEEDIRPEMKEDIHDPTYQDEEG
PPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWS
HRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGW
LLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVN
SLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTF
PFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSS
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| BDBM50371076 |
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| n/a |
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| Name | BDBM50371076 |
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| Synonyms: | CHEMBL229313 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22F3N7O2 |
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| Mol. Mass. | 473.451 |
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| SMILES | FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCc1cnc[nH]1 |
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| Structure | 
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