| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50373489 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_467935 (CHEMBL951044) |
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| Ki | 24700±n/a nM |
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| Citation |  Prante, O; Tietze, R; Hocke, C; Löber, S; Hübner, H; Kuwert, T; Gmeiner, P Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET. J Med Chem51:1800-10 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2 | 5-HT2A | 5HT2A_PIG | HTR2A | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52679.13 |
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| Organism: | PIG |
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| Description: | 5-HT2 0 0::P50129 |
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| Residue: | 470 |
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| Sequence: | MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV
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| BDBM50373489 |
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| n/a |
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| Name | BDBM50373489 |
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| Synonyms: | CHEMBL407818 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N4O |
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| Mol. Mass. | 308.3776 |
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| SMILES | Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 |
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| Structure | 
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