| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50375516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_472907 (CHEMBL922121) |
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| IC50 | 0.3±n/a nM |
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| Citation |  Ashton, TD; Baker, SP; Hutchinson, SA; Scammells, PJ N6-substituted C5'-modified adenosines as A1 adenosine receptor agonists. Bioorg Med Chem16:1861-73 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50375516 |
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| n/a |
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| Name | BDBM50375516 |
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| Synonyms: | CHEMBL258759 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20ClN5O3S |
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| Mol. Mass. | 409.89 |
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| SMILES | O[C@@H]1[C@@H](CCl)O[C@H]([C@@H]1O)n1cnc2c(N[C@H]3C[C@@H]4C[C@@H]3C3SC43)ncnc12 |w:20.22,22.23,THB:14:15:20.22:18,TEB:21:20:18:16.15,21:22:18:16.15| |
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| Structure | 
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