| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine deaminase |
|---|
| Ligand | BDBM50335301 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_702791 (CHEMBL1655234) |
|---|
| Ki | >100000±n/a nM |
|---|
| Citation |  Gillerman, I; Fischer, B Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. J Med Chem54:107-21 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine deaminase |
|---|
| Name: | Adenosine deaminase |
|---|
| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40910.44 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 363 |
|---|
| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
|
|
|
|---|
| BDBM50335301 |
|---|
| n/a |
|---|
| Name | BDBM50335301 |
|---|
| Synonyms: | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(8-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol | CHEMBL1651371 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H14N4O4S |
|---|
| Mol. Mass. | 298.318 |
|---|
| SMILES | CSc1nc2cncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
