| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM50227764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_822294 (CHEMBL2038597) |
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| IC50 | 11.99±n/a nM |
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| Citation |  Méndez-Lucio, O; Pérez-Villanueva, J; Castillo, R; Medina-Franco, JL Activity landscape modeling of PPAR ligands with dual-activity difference maps. Bioorg Med Chem20:3523-32 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
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| Type: | Nuclear Receptor |
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| Mol. Mass.: | 57613.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37231 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
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| BDBM50227764 |
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| n/a |
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| Name | BDBM50227764 |
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| Synonyms: | 2-(4-(3-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)-5-methylphenoxy)-2-methylphenoxy)-2-methylpropanoic acid | CHEMBL237518 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25F4NO5 |
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| Mol. Mass. | 519.4847 |
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| SMILES | Cc1cc(CNC(=O)c2ccc(cc2F)C(F)(F)F)cc(Oc2ccc(OC(C)(C)C(O)=O)c(C)c2)c1 |
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| Structure | 
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