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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Estrogen receptor | ||
| Ligand | BDBM50398933 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_874806 (CHEMBL2188850) | ||
| EC50 | 60±n/a nM | ||
| Citation |  Schäfer, A; Wellner, A; Strauss, M; Schäfer, A; Wolber, G; Gust, R Influence of chlorine or fluorine substitution on the estrogenic properties of 1-alkyl-2,3,5-tris(4-hydroxyphenyl)-1H-pyrroles. J Med Chem55:9607-18 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Estrogen receptor | |||
| Name: | Estrogen receptor | ||
| Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 66230.44 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P03372 | ||
| Residue: | 595 | ||
| Sequence: |
| ||
| BDBM50398933 | |||
| n/a | |||
| Name | BDBM50398933 | ||
| Synonyms: | CHEMBL2178796 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H18FNO3 | ||
| Mol. Mass. | 375.3923 | ||
| SMILES | Cn1c(cc(c1-c1ccc(O)cc1F)-c1ccc(O)cc1)-c1ccc(O)cc1 |(23.78,-8.43,;23.45,-6.92,;22.04,-6.3,;22.2,-4.77,;23.7,-4.44,;24.48,-5.77,;26,-5.93,;26.9,-4.68,;28.43,-4.83,;29.07,-6.24,;30.6,-6.4,;28.17,-7.49,;26.63,-7.34,;25.73,-8.58,;24.32,-3.04,;25.86,-2.88,;26.48,-1.47,;25.57,-.23,;26.19,1.2,;24.03,-.4,;23.41,-1.81,;20.71,-7.08,;19.37,-6.31,;18.04,-7.09,;18.04,-8.63,;16.7,-9.4,;19.37,-9.4,;20.71,-8.63,)| | ||
| Structure | 
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