| Reaction Details |
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 | Report a problem with these data |
| Target | Cruzipain |
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| Ligand | BDBM50421528 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_51850 (CHEMBL664073) |
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| IC50 | 5012±n/a nM |
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| Citation |  Rodrigues, CR; Flaherty, TM; Springer, C; McKerrow, JH; Cohen, FE CoMFA and HQSAR of acylhydrazide cruzain inhibitors. Bioorg Med Chem Lett12:1537-41 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cruzipain |
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| Name: | Cruzipain |
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| Synonyms: | CYSP_TRYCR | Cruzain | Cruzaine | Major cysteine proteinase |
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| Type: | Protein |
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| Mol. Mass.: | 49831.41 |
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| Organism: | Trypanosoma cruzi |
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| Description: | P25779 |
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| Residue: | 467 |
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| Sequence: | MSGWARALLLAAVLVVMACLVPAATASLHAEETLTSQFAEFKQKHGRVYESAAEEAFRLS
VFRENLFLARLHAAANPHATFGVTPFSDLTREEFRSRYHNGAAHFAAAQERARVPVKVEV
VGAPAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDK
TDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL
PQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYW
IIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVGGPGPTPEPTTTTTTSAPGPSPSY
FVQMSCTDAACIVGCENVTLPTGQCLLTTSGVSAIVTCGAETLTEEVFLTSTHCSGPSVR
SSVPLNKCNRLLRGSVEFFCGSSSSGRLADVDRQRRHQPYHSRHRRL
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| BDBM50421528 |
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| n/a |
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| Name | BDBM50421528 |
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| Synonyms: | CHEMBL416237 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8N4O6 |
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| Mol. Mass. | 304.2151 |
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| SMILES | [O-][N+](=O)c1ccc(\C=N\NC(=O)c2cccc(c2)[N+]([O-])=O)o1 |
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| Structure | 
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