| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50029219 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_88769 (CHEMBL857173) |
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| IC50 | 7943±n/a nM |
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| Citation |  Buolamwini, JK; Assefa, H CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site. J Med Chem45:841-52 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50029219 |
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| n/a |
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| Name | BDBM50029219 |
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| Synonyms: | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid 3-phenyl-propyl ester | 3-(3,4-Dihydroxy-phenyl)-acrylic acid 3-phenyl-propyl ester | CHEMBL131982 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18O4 |
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| Mol. Mass. | 298.3331 |
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| SMILES | Oc1ccc(\C=C\C(=O)OCCCc2ccccc2)cc1O |
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| Structure | 
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