| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
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| Ligand | BDBM50196137 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_735955 (CHEMBL1692251) |
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| Ki | 690.24±n/a nM |
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| Citation |  Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M A QSAR study using MTD method and Dragon descriptors for a series of selective ligands ofa2C adrenoceptor. Eur J Med Chem46:877-84 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2C adrenergic receptor |
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| Name: | Alpha-2C adrenergic receptor |
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| Synonyms: | ADA2C_HUMAN | ADRA2C | ADRA2L2 | ADRA2RL2 | Adrenergic alpha2C | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2C-, receptor | Alpha-2 adrenergic receptor subtype C4 | Alpha-2C adrenoceptor | Alpha-2C adrenoreceptor | adrenergic, alpha-2C-, receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 49552.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18825 |
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| Residue: | 462 |
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| Sequence: | MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
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| BDBM50196137 |
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| n/a |
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| Name | BDBM50196137 |
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| Synonyms: | CHEMBL216399 | [4-(4-methylpiperazin-1-yl)phenyl]-(2-methylquinolin-4-yl)-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N4 |
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| Mol. Mass. | 332.4421 |
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| SMILES | CN1CCN(CC1)c1ccc(Nc2cc(C)nc3ccccc23)cc1 |
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| Structure | 
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