| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM22496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_770381 (CHEMBL1833690) |
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| EC50 | 47.86±n/a nM |
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| Citation |  Christiansen, E; Urban, C; Grundmann, M; Due-Hansen, ME; Hagesaether, E; Schmidt, J; Pardo, L; Ullrich, S; Kostenis, E; Kassack, M; Ulven, T Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem54:6691-703 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM22496 |
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| n/a |
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| Name | BDBM22496 |
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| Synonyms: | 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid | CHEMBL207881 | carboxylic acid agonist, 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21NO3 |
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| Mol. Mass. | 347.407 |
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| SMILES | OC(=O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1 |
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| Structure | 
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