| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent GABA transporter 1 |
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| Ligand | BDBM50419338 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_788594 (CHEMBL1918629) |
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| IC50 | 10233±n/a nM |
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| Citation |  Schaffert, ES; Höfner, G; Wanner, KT Aminomethyltetrazoles as potential inhibitors of the¿-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. Bioorg Med Chem19:6492-504 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium- and chloride-dependent GABA transporter 1 |
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| Name: | Sodium- and chloride-dependent GABA transporter 1 |
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| Synonyms: | GABA transporter | GABA transporter 1 | Gabt1 | Gat-1 | Gat1 | SC6A1_MOUSE | Slc6a1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 67006.26 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_788602 |
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| Residue: | 599 |
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| Sequence: | MATDNSKVADGQISTEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGY
AIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAP
MFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSLV
NTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVV
YFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGL
GSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASG
PGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRR
ELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF
YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLM
ALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPENGPEQPQAGSSASKEAYI
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| BDBM50419338 |
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| n/a |
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| Name | BDBM50419338 |
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| Synonyms: | CHEMBL1446457 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N2O2 |
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| Mol. Mass. | 414.5393 |
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| SMILES | COc1ccccc1C1(O)CCN(CCCn2c3ccccc3c3ccccc23)CC1 |
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| Structure | 
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