| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50421924 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_60934 |
|---|
| IC50 | 288±n/a nM |
|---|
| Citation |  Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Benz[f]isoquinoline analogues as high-affinity sigma ligands. J Med Chem35:2025-33 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50421924 |
|---|
| n/a |
|---|
| Name | BDBM50421924 |
|---|
| Synonyms: | CHEMBL544280 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H31N |
|---|
| Mol. Mass. | 333.5096 |
|---|
| SMILES | CC(C)(C)c1ccc(CN2CC[C@@H]3[C@@H](CCc4ccccc34)C2)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
