| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 1 |
|---|
| Ligand | BDBM50423318 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_456079 (CHEMBL888088) |
|---|
| Kd | 6.0±n/a nM |
|---|
| Citation |  Troxler, T; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Schoeffter, P; Sorg, D; Swoboda, R; Hurth, K Identification and SAR of potent and selective non-peptide obeline somatostatin sst1 receptor antagonists. Bioorg Med Chem Lett17:3983-7 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 1 |
|---|
| Name: | Somatostatin receptor type 1 |
|---|
| Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS1R | SSR1_RAT | Somatostatin receptor | Somatostatin receptor type 1 | Sstr1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42752.93 |
|---|
| Organism: | RAT |
|---|
| Description: | SOMATOSTATIN SST1 SSTR1 RAT::P28646 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCASRISTL
|
|
|
|---|
| BDBM50423318 |
|---|
| n/a |
|---|
| Name | BDBM50423318 |
|---|
| Synonyms: | CHEMBL251752 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H32N4O4 |
|---|
| Mol. Mass. | 476.5674 |
|---|
| SMILES | CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3C(C)=O)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
