| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil collagenase |
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| Ligand | BDBM50062478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458937 (CHEMBL924956) |
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| Ki | 537±n/a nM |
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| Citation |  Verma, RP; Hansch, C Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioorg Med Chem15:2223-68 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutrophil collagenase |
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| Name: | Neutrophil collagenase |
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| Synonyms: | CLG1 | MMP-8 | MMP8 | MMP8_HUMAN | Matrix metalloproteinase-8 | Neutrophil collagenase precursor | PMNL collagenase | PMNL-CL |
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| Type: | Enzyme |
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| Mol. Mass.: | 53413.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22894 |
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| Residue: | 467 |
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| Sequence: | MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV
EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY
TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL
AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA
FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD
RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG
YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI
ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
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| BDBM50062478 |
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| n/a |
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| Name | BDBM50062478 |
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| Synonyms: | CHEMBL116641 | N-Hydroxy-2-isobutyl-N'-(3-phenyl-propyl)-malonamide | N1-hydroxy-2-isobutyl-N3-(3-phenylpropyl)malonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24N2O3 |
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| Mol. Mass. | 292.3734 |
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| SMILES | CC(C)CC(C(=O)NO)C(=O)NCCCc1ccccc1 |
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| Structure | 
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