| Reaction Details |
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 | Report a problem with these data |
| Target | Purine nucleoside phosphorylase |
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| Ligand | BDBM27504 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_641938 (CHEMBL1176015) |
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| Kd | 316228±n/a nM |
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| Citation |  Ducati, RG; Basso, LA; Santos, DS; de Azevedo, WF Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis. Bioorg Med Chem18:4769-74 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Purine nucleoside phosphorylase |
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| Name: | Purine nucleoside phosphorylase |
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| Synonyms: | Inosine phosphorylase | Inosine-guanosine phosphorylase | MT3406 | PNP | PUNA_MYCTU | deoD | punA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27567.15 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | ChEMBL_641938 |
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| Residue: | 268 |
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| Sequence: | MADPRPDPDELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTTVLPQAELPGF
VPPTAAGHAGELLSVPIGAHRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNA
AGGLRADLQVGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGVY
AGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEP
LSHAEVLAAGAASATRMGALLADVIARF
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| BDBM27504 |
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| n/a |
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| Name | BDBM27504 |
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| Synonyms: | 4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quinazolin-4-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C8H6N2O |
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| Mol. Mass. | 146.146 |
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| SMILES | O=c1[nH]cnc2ccccc12 |
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| Structure | 
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