Reaction Details | |||
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Target | N-arachidonyl glycine receptor | ||
Ligand | BDBM50448075 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1292267 (CHEMBL3124698) | ||
IC50 | 9910±n/a nM | ||
Citation | Harms, H; Rempel, V; Kehraus, S; Kaiser, M; Hufendiek, P; Müller, CE; König, GM Indoloditerpenes from a marine-derived fungal strain of Dichotomomyces cejpii with antagonistic activity at GPR18 and cannabinoid receptors. J Nat Prod77:673-7 (2014) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
N-arachidonyl glycine receptor | |||
Name: | N-arachidonyl glycine receptor | ||
Synonyms: | G-protein coupled receptor 18 | GPCRW | GPR18 | GPR18_HUMAN | NAGly receptor | ||
Type: | PROTEIN | ||
Mol. Mass.: | 38150.44 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_107601 | ||
Residue: | 331 | ||
Sequence: |
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BDBM50448075 | |||
n/a | |||
Name | BDBM50448075 | ||
Synonyms: | CHEMBL1258979 | ||
Type | Small organic molecule | ||
Emp. Form. | C28H37NO | ||
Mol. Mass. | 403.5995 | ||
SMILES | CC(C)=C[C@H]1C[C@]2(C)[C@H](CC[C@@]3(C)[C@H]2CC[C@H]2Cc4c([nH]c5ccccc45)[C@]32C)O1 |r,wU:11.11,6.6,8.33,13.14,wD:16.17,27.32,4.3,(32.2,-12.88,;30.67,-12.87,;29.92,-11.54,;29.89,-14.18,;28.36,-14.17,;27.46,-12.9,;25.97,-13.36,;25.95,-11.85,;25.95,-14.93,;24.6,-15.69,;23.27,-14.91,;23.28,-13.37,;23.27,-11.84,;24.63,-12.61,;24.63,-11.06,;23.29,-10.28,;21.95,-11.05,;20.48,-10.57,;19.59,-11.84,;20.48,-13.08,;19.57,-14.32,;18.11,-13.84,;16.79,-14.61,;15.46,-13.84,;15.46,-12.31,;16.78,-11.54,;18.11,-12.3,;21.95,-12.6,;21.94,-14.13,;27.43,-15.42,)| | ||
Structure |