| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50453055 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58818 (CHEMBL857791) |
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| Ki | 912±n/a nM |
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| Citation |  Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML Synthesis and antidopaminergic activity of some 3-(aminomethyl)tetralones as analogues of butyrophenone. J Med Chem34:2242-7 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50453055 |
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| n/a |
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| Name | BDBM50453055 |
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| Synonyms: | CHEMBL72649 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28F2N2O2 |
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| Mol. Mass. | 426.4988 |
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| SMILES | Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccc(F)cc3C2)CC1 |
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| Structure | 
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