| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium-dependent serotonin transporter |
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| Ligand | BDBM50010307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1340419 (CHEMBL3253107) |
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| IC50 | 900±n/a nM |
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| Citation |  Carnmalm, B; Rämsby, S; Renyi, AL; Ross, SB; Ogren, SO Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants. J Med Chem21:78-82 (1978) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium-dependent serotonin transporter |
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| Name: | Sodium-dependent serotonin transporter |
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| Synonyms: | 5-HT Transporter | 5HT transporter | 5HTT | Htt | SC6A4_MOUSE | Serotonin transporter | Sert | Slc6a4 | Sodium-dependent serotonin transporter | Solute carrier family 6 member 4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70044.92 |
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| Organism: | MOUSE |
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| Description: | 5-HT Transporter SLC6A4 MOUSE::Q60857 |
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| Residue: | 630 |
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| Sequence: | METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAGPGQISNGYSAVPSTSAGDEAP
HSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLP
YTIMAIFGGIPLFYMELALGQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTII
AWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIH
QSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGA
TLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQD
ALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPAS
TFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLT
LTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRIC
WVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLIST
PGTLKERIIKSITPETPTEIPCGDIRMNAV
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| BDBM50010307 |
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| n/a |
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| Name | BDBM50010307 |
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| Synonyms: | CHEMBL3251303 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22ClN |
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| Mol. Mass. | 287.827 |
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| SMILES | Cl.CN(C)C1CC(C1)(c1ccccc1)c1ccccc1 |
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| Structure | 
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