| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50049459 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1450299 (CHEMBL3377010) |
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| IC50 | 100000±n/a nM |
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| Citation |  Afzal, O; Kumar, S; Kumar, R; Firoz, A; Jaggi, M; Bawa, S Docking based virtual screening and molecular dynamics study to identify potential monoacylglycerol lipase inhibitors. Bioorg Med Chem Lett24:3986-96 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50049459 |
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| n/a |
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| Name | BDBM50049459 |
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| Synonyms: | CHEMBL3318314 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N4O3 |
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| Mol. Mass. | 390.4351 |
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| SMILES | Cc1ccc(cc1C)N1C[C@@H](CC1=O)C(=O)NCc1n[nH]c(=O)c2ccccc12 |r| |
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| Structure | 
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