| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-U receptor 2 |
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| Ligand | BDBM50102659 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1442319 (CHEMBL3377680) |
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| EC50 | 47000±n/a nM |
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| Citation |  Ma, ML; Li, M; Gou, JJ; Ruan, TY; Jin, HS; Zhang, LH; Wu, LC; Li, XY; Hu, YH; Wen, K; Zhao, Z Design, synthesis and biological activity of flavonoid derivatives as selective agonists for neuromedin U 2 receptor. Bioorg Med Chem22:6117-23 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-U receptor 2 |
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| Name: | Neuromedin-U receptor 2 |
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| Synonyms: | G-protein coupled receptor FM-4 | G-protein coupled receptor TGR-1 | NMU-R2 | NMU2R | NMU2R | NMUR2 | NMUR2_HUMAN | Neuromedin-U receptor 2 | TGR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47710.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_103075 |
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| Residue: | 415 |
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| Sequence: | MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGV
IGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCY
FKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLP
NTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMA
LRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSES
LAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPA
QRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPAALSSEQMSRTNYQSFHFNKT
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| BDBM50102659 |
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| n/a |
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| Name | BDBM50102659 |
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| Synonyms: | CHEMBL3343023 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12BrFO4 |
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| Mol. Mass. | 379.177 |
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| SMILES | OCCOc1c(oc2ccccc2c1=O)-c1cc(Br)ccc1F |
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| Structure | 
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