Reaction Details |
| Report a problem with these data |
Target | Tegument protein VP16 |
---|
Ligand | BDBM87260 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
---|
IC50 | 8009±n/a nM |
---|
Citation | PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Tegument protein VP16 |
---|
Name: | Tegument protein VP16 |
Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
Type: | PROTEIN |
Mol. Mass.: | 54325.13 |
Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
Description: | EBI_100271 |
Residue: | 490 |
Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
|
|
|
BDBM87260 |
---|
n/a |
---|
Name | BDBM87260 |
Synonyms: | 5-(4-chlorophenyl)-N-(2-morpholin-4-ylethyl)thieno[2,3-d]pyrimidin-4-amine | 5-(4-chlorophenyl)-N-[2-(4-morpholinyl)ethyl]-4-thieno[2,3-d]pyrimidinamine | MLS000528887 | SMR000121362 | [5-(4-Chloro-phenyl)-thieno[2,3-d]pyrimidin-4-yl]-(2-morpholin-4-yl-ethyl)-amine | [5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-(2-morpholinoethyl)amine | cid_1078331 |
Type | Small organic molecule |
Emp. Form. | C18H19ClN4OS |
Mol. Mass. | 374.888 |
SMILES | Clc1ccc(cc1)-c1csc2ncnc(NCCN3CCOCC3)c12 |
Structure |
|