| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
|---|
| Ligand | BDBM40936 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose-response confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay |
|---|
| IC50 | >66000±n/a nM |
|---|
| Citation |  PubChem, PC Dose-response confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Polyadenylate-binding protein 1 |
|---|
| Name: | Polyadenylate-binding protein 1 |
|---|
| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 70694.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_46367787 |
|---|
| Residue: | 636 |
|---|
| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
|
|
|
|---|
| BDBM40936 |
|---|
| n/a |
|---|
| Name | BDBM40936 |
|---|
| Synonyms: | (2-Cyclopropyl-quinazolin-4-ylsulfanyl)-acetic acid ethyl ester | 2-[(2-cyclopropyl-4-quinazolinyl)thio]acetic acid ethyl ester | 2-[(2-cyclopropylquinazolin-4-yl)thio]acetic acid ethyl ester | MLS000073695 | SMR000003745 | cid_644454 | ethyl 2-(2-cyclopropylquinazolin-4-yl)sulfanylacetate | ethyl 2-(2-cyclopropylquinazolin-4-yl)sulfanylethanoate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H16N2O2S |
|---|
| Mol. Mass. | 288.365 |
|---|
| SMILES | CCOC(=O)CSc1nc(nc2ccccc12)C1CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
