Reaction Details |
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Target | Corticotropin-releasing factor-binding protein |
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Ligand | BDBM90193 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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EC50 | >53000±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Corticotropin-releasing factor-binding protein |
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Name: | Corticotropin-releasing factor-binding protein |
Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36143.95 |
Organism: | Homo sapiens (Human) |
Description: | P24387 |
Residue: | 322 |
Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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BDBM90193 |
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n/a |
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Name | BDBM90193 |
Synonyms: | MLS000335120 | N-[1-(1H-benzimidazol-2-yl)-2-phenyl-ethyl]-4-chloranyl-3-nitro-benzamide | N-[1-(1H-benzimidazol-2-yl)-2-phenyl-ethyl]-4-chloro-3-nitro-benzamide | N-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-4-chloro-3-nitrobenzamide | SMR000249878 | cid_3320062 |
Type | Small organic molecule |
Emp. Form. | C22H17ClN4O3 |
Mol. Mass. | 420.848 |
SMILES | [O-][N+](=O)c1cc(ccc1Cl)C(=O)NC(Cc1ccccc1)c1nc2ccccc2[nH]1 |
Structure |
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