| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM90463 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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| EC50 | 44200±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM90463 |
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| n/a |
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| Name | BDBM90463 |
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| Synonyms: | 8-[4-(dimethylamino)benzylidene]-6,10-dioxaspiro[4.5]decane-7,9-quinone | 8-[[4-(dimethylamino)phenyl]methylidene]-6,10-dioxaspiro[4.5]decane-7,9-dione | MLS000678321 | SMR000285277 | cid_765996 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19NO4 |
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| Mol. Mass. | 301.3371 |
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| SMILES | [#6]-[#7](-[#6])-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#8]C3([#6]-[#6]-[#6]-[#6]3)[#8]-[#6]-2=O)cc1 |
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| Structure | 
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