| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM34922 |
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| Substrate/Competitor | n/a |
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| IC50 | 7060±519 nM |
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| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM34922 |
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| n/a |
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| Name | BDBM34922 |
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| Synonyms: | 3-(3-methylolanilino)-5-nitro-indol-2-one | 3-[3-(hydroxymethyl)anilino]-5-nitro-2-indolone | 3-[3-(hydroxymethyl)anilino]-5-nitroindol-2-one | 3-[[3-(hydroxymethyl)phenyl]amino]-5-nitro-indol-2-one | MLS000710735 | SMR000280502 | cid_3109108 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11N3O4 |
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| Mol. Mass. | 297.2655 |
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| SMILES | OCc1cccc(c1)\[NH+]=C1/C(=O)[N-]c2ccc(cc12)[N+]([O-])=O |
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| Structure | 
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