| Reaction Details |
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 | Report a problem with these data |
| Target | Protein skinhead-1 |
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| Ligand | BDBM93819 |
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| Substrate/Competitor | n/a |
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| IC50 | 22700±n/a nM |
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| Citation |  PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein skinhead-1 |
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| Name: | Protein skinhead-1 |
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| Synonyms: | SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70701.17 |
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| Organism: | Caenorhabditis elegans |
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| Description: | P34707 |
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| Residue: | 623 |
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| Sequence: | MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVIS
SPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYD
YPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSR
YEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENAR
YEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLF
EDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTT
STAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHS
YQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSS
TCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLAS
GQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGK
NKVAARTCRQRRTDRHDKMSHYI
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| BDBM93819 |
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| n/a |
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| Name | BDBM93819 |
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| Synonyms: | (E)-3-(2,4-difluoroanilino)-1-(2-furanyl)-2-propen-1-one | (E)-3-(2,4-difluoroanilino)-1-(2-furyl)prop-2-en-1-one | (E)-3-(2,4-difluoroanilino)-1-(furan-2-yl)prop-2-en-1-one | (E)-3-[[2,4-bis(fluoranyl)phenyl]amino]-1-(furan-2-yl)prop-2-en-1-one | 3-[(2,4-difluorophenyl)amino]-1-(2-furyl)-2-propen-1-one | MLS000662236 | SMR000293131 | cid_2196922 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9F2NO2 |
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| Mol. Mass. | 249.2129 |
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| SMILES | Fc1ccc(N=CCC(=O)c2ccco2)c(F)c1 |w:5.4| |
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| Structure | 
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